He's featured in the Fallout: New Vegas add-on Dead Money (released December 21, 2010).
Slowly revealed through the course of the game is that Domino groomed actress/singer Vera Keyes, then blackmailed her to get chummy with wealthy businessman Frederick Sinclair, and get Sinclair to fall in love with her. Then Domino would use his access via Keyes to rob Sinclair's Sierra Madre casino.
Dean, Vera Keyes, and Joey Baxter were to perform at the Tampico Theater in the Sierra Madre resort for it's gala opening event, but that turned out to be the day World War III started, ending civilization.
There's a holographic clip of him singing the 1954 song "Something's Gotta Give."
After the war, Dean turned into a "ghoul," meaning radiation turned him into a disfigured zombie-like mutant, but with a very long life. It did not affect his British accent, charm, or fragile ego, however.